The SAIFERM wave bioreactor is specially developed for cell culture enterprises, and is used in conjunction with disposable cell culture bags or sheet-like carrier bags to achieve efficient gas-liquid and substance exchange in a closed system by simulating wave oscillation.
The SAIFERM wave bioreactor, in conjunction with a self-developed software system, can monitor real-time parameters such as pH, DO, and weight during the cultivation process through a control platform. It can also set parameters such as swing speed, swing angle, temperature, pH, DO, ventilation rate, and gas component concentration during the cultivation process to meet the requirements of production enterprises for real-time monitoring, flexible adjustment, and optimization of process parameters.
The SAIFERM wave bioreactor also has a unique cascade design that can correlate parameters during the reaction process, such as weight and peristaltic pump operation, pH and carbon dioxide concentration changes. Through concise and intuitive logic, automated operations are achieved, reducing manual intervention, minimizing human errors, and ultimately reducing labor costs in the long run.
Single Use Bioreactor Bag
Characteristics of 2D bags: good film stability; Good chemical compatibility and biocompatibility; Meet the storage and transportation of various solutions in biopharmaceutical processes; Flexible customization of size and pipeline, convenient and fast.
Advantages of 2D bags: The product is produced in IS07/IS05 grade; All products undergo 100% leak testing before leaving the factory; Can be directly transported for freezing and thawing; We can customize production according to customer needs.
Application of 2D bags: storage and transportation of culture media; Storage and transportation of buffer solution; Collection and storage of samples and components; Storage of intermediate and semi-finished products.
Features
Save floor space
A controller paired with two trays greatly saves space.
Compatible with various specifications of culture bags
The bag size (working volume) covers from 500ml (50ml) to 50L (25L).
Can be used for raw material screening
Each 10L tray can hold 3 500mL bags, and the same conditions can be used for screening raw materials such as microcarriers and culture media.
Easy to scale up the process
The tray can be replaced (with 10L, 20L, 50L trays), and the dual tray configuration can quickly transfer and enlarge the cultured seed cells. One device can meet all the needs from small-scale research and development to pilot/production.
Intelligent control system
Equipped with a self-developed high-precision control system, it can monitor and adjust various parameters during the cultivation process in real time, perform data collection, real-time curve recording, historical record tracing, result comparison, and report printing, in compliance with GMP regulations.
One control and two design
Each tray can accommodate single or more cell culture bags for operation and cultivation, and can be flexibly adjusted according to different cell types and cultivation needs. One set of equipment can accommodate 4-12 culture bags, optimizing space utilization, improving work efficiency, and reducing operating costs.
Automated operation
It can correlate parameters in the reaction process, such as weight and peristaltic pump operation, pH and carbon dioxide concentration changes, and achieve automated operation through concise and intuitive logic, reducing manual intervention and human error, and ultimately reducing labor costs.
Equipped with an independent disposable consumables production line
All supporting suspension cell culture bags, retention membrane cell culture bags, sheet-like carrier cell culture bags, and related storage bags are completely independently produced by Saikecheng, with complete verification documents to ensure continuous supply of consumables.
Parameter
Tray size | 10L | 20L | 50L | ||
Total volume (suspension culture) | 2L | 5L | 10L | 20L | 50L |
Total volume (adherent culture) | 2L | 5L | 10L | 20L | 50L |
Max. working volume | IL | 2.5L | 5L | 10L | 25L |
Control system | Siemens PLC, 15-inch color touch screen, Ethernet interface, USB interface | ||||
Temperature control | Heating plate, PID automatic control, accuracy: ±0.2°C; Temperature control range: 5-40°C above | ||||
Rocker speed | l-40rpm | ||||
Tilt angle | 1-12° | ||||
Gas※ | 3 thermal mass flow controllers (Air/O2/CO2), 1 thermal mass flow controller with 3 gas mixer optional | ||||
Exhaust ※ | Exhaust condenser, exhaust filter heater optional | ||||
Exhaust analysis | O2(0-50%), CO2 (0-15%) | ||||
Pressure detection | Range:-100mbar——l00mbar; Stop air intake when it is exceeded. | ||||
pH | Single-use pH probe, control range: 6-8, accuracy:±0.05pH; PID control; cascaded by gas flow, peristaltic pump, etc. | ||||
DO | Single-use DO probe, control range: 0-100%, accuracy:±3%; PID control; cascaded by rocker speed, MFC, etc. | ||||
Pumps※ | 4fixed-speed peristaltic pumps,customized feeding/acid feeding/alkali feeding/ discharging etc. 25RPM or 100RPM variable speed optional | ||||
Load cell | Load: 0-50kg, accuracy: ± (0.050 +1% loading sampling) kg; cascaded by pumps | ||||
Utilities | Air/O2/CO2, pressure: 15-20PSIG | ||||
Signal interface | Optional | ||||
Power supply | AC220V,50/60HZ, 10A | ||||
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